H. Başpinar Küçük, T. Yildiz, Y. Arasan et al., R. O. Akar et al. — Evaluation of Anticancer Activity of Novel Sulfanyl-Substituted Hydrazone Compounds in Hepatocellular Carcinoma: In Vitro, In Silico, and In Ovo Studies
ACS Omega · DOI: 10.1021/acsomega.5c13125
S. Malcanlı, R. O. Akar, E. Ulukaya, A. B. Özkaya, Ö. G. Geyik — Enhancing 5-fluorouracil efficacy in colorectal cancer by inhibiting glutathione antioxidant mechanisms with an xCT inhibitor
Scientific Reports · DOI: 10.1038/s41598-026-41179-x
L. Alparslan, S. Özdemir, B. Karacan, R. O. Akar et al. — Formulation and Characterization of an Oleuropein-Enriched Oral Spray Gel: Microbiological Performance and In Ovo Histopathological Safety
Pharmaceutics · DOI: 10.3390/pharmaceutics18020200
M. Ekremoğlu, R. O. Akar, C. Altınkaynak, B. P. Kutluay, E. Ulukaya — Enhancing Anti-Angiogenic Therapy With Bevacizumab-Based Nanoflowers through the Chorioallantoic Membrane Assay
ChemistrySelect · DOI: 10.1002/slct.202504665
N. Alhalak, A. Şen, G. N. Öter, R. O. Akar, T. Şekerler — Anti-Angiogenic and Cytotoxic Potential of Different Eremurus spectabilis Extracts on Hepatocellular Carcinoma (Hep3B) Cells: In vitro, In Ovo and In silico Study
Computers in Biology and Medicine · DOI: 10.1016/j.compbiomed.2025.110498
O. Nejati, G. Torkay, A. Girgin, R. O. Akar et al. — Biocompatible silver nanoparticles from apricot kernel skin: green synthesis for antibacterial and antiangiogenic therapies
Chemical Papers · DOI: 10.1007/s11696-024-03793-9
A. Bal-Öztürk, G. Torkay, N. İdil, R. O. Akar et al. — Propolis-loaded photocurable methacrylated pullulan films: Mechanical, antibacterial, biocompatibility, wound healing and pro-angiogenic evaluation
International Journal of Biological Macromolecules · DOI: 10.1016/j.ijbiomac.2024.137071
C. Icsel, V. T. Yilmaz, M. Aygun, M. Erkisa, E. Ulukaya, R. O. Akar — Pd(II) and Pt(II) saccharinate complexes with phosphine derivatives: Synthesis, anticancer and antiangiogenic activities
Applied Organometallic Chemistry · DOI: 10.1002/aoc.7433
K. Adacan, Z. Gokmen, R. O. Akar, Z. Ozyıldız, H. Dinçer, D. Karakaş, E. Ulukaya — Synthesis, Characterization and Apoptosis Capabilities of a Novel Naphthoquinone-Derived Compound in Triple-Negative Breast Cancer
ChemistrySelect · DOI: 10.1002/slct.202301955
D. Karakas, M. Erkisa, R. O. Akar, G. Akman, E. Y. Senol, E. Ulukaya — Targeting Periostin Expression Makes Pancreatic Cancer Spheroids More Vulnerable to Natural Killer Cells
Biomedicines · DOI: 10.3390/biomedicines11020270
Z. Gerçek, U. Yıldız, R. O. Akar, E. Ulukaya — Selective Cytotoxicity of Novel Copper(II) Complex on Colon Cancer Cell Lines
European Journal of Advanced Chemistry Research · DOI: 10.24018/ejchem.2022.3.3.115
M. Erkisa-Genel, S. Selvi, I. Yilmaz, R. O. Akar, I. Yaylim, A. Şengül, E. Ulukaya — Differential Cytotoxic Activity of a New Cationic Pd(II) Coordination Compound in Cancer Cell Lines
Experimed · DOI: 10.26650/experimed.1188586
R. O. Akar, İ. Yılmaz, M. Erkısa, A. Şengül, E. Ulukaya — Highly Promising Antitumor Agent of a Novel Platinum(II) Complex Bearing a Tetradentate Chelating Ligand
ACS Medicinal Chemistry Letters · DOI: 10.1021/acsmedchemlett.9b00676
S. Bozkurt, F. Yarımcan, H. Ayhan, R. O. Akar, V. S. Hançer et al. — Investigation of PTGS2, MAGE-A3, CALR, KRT19 and TMPRSS4 expressions in HCT116 and PC3 cancer cell lines
Genetics & Applications · DOI: 10.31383/ga.vol4iss2pp37-42
E. D. Arısan, R. O. Akar, Ö. Rencuzogullari et al. — Molecular targets of diclofenac vs. ibuprofen differ in inducing apoptosis and EMT via oxidative stress management in PC3 prostate cancer cells
Prostate International · DOI: 10.1016/j.prnil.2019.09.003
Z. Gercek, U. Yıldız, E. Ulukaya, R. O. Akar — Synthesis, DNA binding and cytotoxic activity of new copper(II) complexes of trisubstituted imidazoles
Pharmaceutical Chemistry Journal · DOI: 10.1007/s11094-022-02578-2
D. Karakas, R. O. Akar, Z. Gokmen, N. G. Deniz, E. Ulukaya — A Novel 1,4-Naphthoquinone-Derived Compound Induces Mitochondria-Mediated Apoptotic Cell Death in Breast Cancer Cells
Turkish Journal of Biology · DOI: 10.3906/biy-1901-19
R. O. Akar, S. Selvi, E. Ulukaya, N. Aztopal — Key actors in cancer therapy: Epigenetic modifiers (Review)
Turkish Journal of Biology · DOI: 10.3906/biy-1903-39
M. Erkisa, S. Aydinlik, B. Cevatemre, N. Aztopal, R. O. Akar et al. — A promising combination for metastatic prostate cancer: Chloroquine as autophagy inhibitor and Pd(II) barbiturate complex
Biochimie · DOI: 10.1016/j.biochi.2020.05.010
Conference Presentations
M. Ekremoğlu, R. O. Akar, C. Altınkaynak, E. Ulukaya — Toxicity and Anti-Angiogenic Effects of Bevacizumab, Adalimumab, Infliximab and Combinations by In Ovo CAM Assay (Poster) EUROTOX 2025, Athens · DOI: 10.1016/j.toxlet.2025.07.446
G. N. Öter, R. O. Akar, A. Şen, E. Ulukaya, C. Küçükgergin — Anti-cancer effect of Myrtus communis extract against lung adenocarcinoma in vitro and in ovo (Poster) 48th FEBS Congress, Milano 2024
B. H. Şahin, T. Doğan, R. O. Akar, M. Acar, P. Ata — Apoptotic and Antiproliferative Effects of Geraniol on PC-3 Prostate Cancer Cells (Oral) 2024
R. O. Akar, M. Ekremoğlu, C. Altınkaynak, E. Ulukaya — Bevacizumab-loaded Nanoflowers: Inhibitory Effect on Neovascularization in ovo CAM Assay (Poster) EUROTOX 2023, Ljubljana · DOI: 10.1016/S0378-4274(23)00767-1
R. O. Akar, K. Adacan, E. Ulukaya — In ovo: Dinosaur's Offspring as an Alternative In Vivo Model (Oral) 2nd International Multidisciplinary Cancer Research Congress, Giresun 2022
D. Karakas Zeybek, M. Erkisa, R. O. Akar, E. Ulukaya — Targeting Pancreatic Cancer Stroma Increases NK Cell-Mediated Cytotoxicity in Spheroid Tumor Microenvironment (Poster) FEBS 2022, Lisbon
M. Erkisa, R. O. Akar, S. Selvi, E. Ulukaya, A. Şengül — A Newly Synthesized Platinum Complex as a Potent Antitumor Drug Candidate (Poster) International Molecular Medicine Symposium, Bahçeşehir University 2019
R. O. Akar, Ö. Rencuzogullari, E. D. Arısan et al. — Diclofenac Increased ROS Generation to Proceed EMT Processes p53-Independently in PC3 Cells (Poster) 6th Stem Cell Symposium, Marmara University 2017